IN-VIVO ANTIDIARRHOEAL ACTIVITY OF EXTRACTS FROM STEM BARK OF Saraca Asoca Roxb. PREPARED BY DIFFERENT EXTRACTION METHODS
نویسنده
چکیده
Dried stem bark extracts of Saraca asoca Roxb. Prepared by different extraction methods (Soxhlet, Ultrasonication assisted & Microwave assisted extraction) with ethanol 90%, ethanol 60% and acetone. The acetone extract prepared by Ultrasonication assisted extraction, showed significant antidiarrhoeal property in castor-oil induced diarrhoea in albino rats at a dose of 200 mg/kg, b.w. as compared to standard drug loperamide at a dose of 3 mg/kg, b.w. The preliminary phytochemical screening of extracts of stem bark of Saraca asoca results with the presence of alkaloids, tannins, flavonoids and phenolic compounds etc. The result obtained establishes the efficacy and substantiate the folklore claim as an antidiarrhoeal agent. Further studies are needed to completely understand the mechanism of antidiarrhoeal action of Saraca asoca Roxb.
منابع مشابه
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